Abraham Lincoln Delivered A Two Minute Proclamation Of Our...

Seven score and eleven years ago Abraham Lincoln delivered a two minute proclamation of our Nation s purpose. In just over two minutes President Lincoln clearly stated that slavery would no longer endure in the United States, and acknowledging the sacrifices of both the Confederacy and the Union. He was able to pivot the Civil War to mean more than a states rights conflict and the power of the federal government to be about equality and the â€Å"a new birth of freedom† (Baym). Lincoln s ability to speak with expressive style and enthusiasm lead to a victory for the Union. Lincoln s ability to use imagery and metaphors is what made his writing so persuasive. He was able to use this persuasiveness take a moral high ground for his cause and turn the tide of the Civil War to his favor. The ordinary backgrounds of influential people have always captured the minds of the American people as it speaks to our unique American culture of pulling yourself up by your boot straps and maki ng something of yourself, and Lincoln was no exception. Lincoln spent most of his life supporting his family and had little to none formal education. What Lincoln lost in the halls of the ivory towers he gained in practical experience working on farms and shops. He learned how to speak to everyday Americans. Lincoln was able to use his humble beginnings to connect with people by saying, â€Å"I am not ashamed to confess that twenty-five years ago I was a hired laborer, mauling rails, at work on a flat boat –Show MoreRelatedThe Legacy Of Abraham Lincoln1837 Words   |  8 Pages Honest Abe Abraham Lincoln was born on February 12th, 1809 in a log cabin in Kentucky. He was raised by poor parents and received less than a year of formal education. He was mainly self-educated by reading a lot of books on his own. Lincoln was known for being an opponent of slavery. He was the 16th president of the United States and served from March 1861 until he was assassinated in April of 1865. His main accomplishments include leading the United States through the Civil War and abolishingRead MoreOne Significant Change That Has Occurred in the World Between 1900 and 2005. Explain the Impact This Change Has Made on Our Lives and Why It Is an Important Change.163893 Words   |  656 Pagesan Urban World †¢ Howard Spodek 53 3 Women in the Twentieth-Century World Bonnie G. Smith 83 4 The Gendering of Human Rights in the International Systems of Law in the Twentieth Century †¢ Jean H. Quataert 116 5 The Impact of the Two World Wars in a Century of Violence †¢ John H. Morrow Jr. 161 6 Locating the United States in Twentieth-Century World History †¢ Carl J. Guarneri 213 7 The Technopolitics of Cold War: Toward a Transregional Perspective †¢ Gabrielle Hecht

What Are The Limitations Of Delivering Vaccines - 2953 Words

What are the limitations of delivering vaccines nasally? Abstract Intranasal vaccinations are a developing area of research that can provide a promising alternative to the current strategy of intramuscular injections 1. In this review, the reasons for growing interest in intranasal administration are discussed, with those relating specifically to vaccinations being considered in more detail. In addition, the main limitations to nasal vaccines are reviewed, taking into account issues with the nasal mucosa and the vaccine formulation itself. Finally, nasal vaccinations that are currently available are discussed as well as the potential future developments in the field. Introduction Vaccinations are the cornerstone of preventing and†¦show more content†¦Since then, research in this area has been driven to overcome the issues with nasal vaccines and broaden their use as viable immunological tools. Interest in Intranasal Administration The nasal route has been extensively used for topical treatments in the past, for example, in the treatment of rhinitis with antihistamines. However, due to the appealing drug absorption potential of the nasal mucosa, intranasal administration for the systemic delivery of drugs has grown in popularity, allowing it to be considered as an alternative parenteral route of administration 11. The nasal mucosa consists of pseudostratified columnar epithelium that lies on top of a highly vascularised basement membrane. The columnar cell surface possesses microvilli which extensively aid systemic absorption through a greatly increased surface area 5. The highly vascularised mucosa plays a significant role in systemic absorption as blood flow, and subsequently the concentration gradient across the membrane, has a major influence in the absorption of drugs into the systemic circulation 1. These anatomical aspects, coupled with the nasal cavity’s thin and porous endothelial membrane prov ide an attractive option for a range of therapeutic applications 5. An example of such an application is the administration of fentanyl. Nasal delivery of fentanyl exhibits a rapid onset of action due to the advantageous nasal anatomy and provides a Tmax of approximately 7 minutes, aShow MoreRelatedCauses And Treatments Of Gene Therapy1740 Words   |  7 Pagesprevented through vaccines. However, there are still many other diseases that can’t be cured. Many diseases have drugs and medicine that can help relieve or regulate symptoms of different medical conditions and disorders, but they do not help fix the problem at its source. However, a form of genetic engineering may soon be able to treat these problems. Gene therapy has the potential to be able to treat and cure many diseases and disorders, but it does not come without limitations and downsides. GeneRead MoreThe Origin Of The Word Nano1593 Words   |  7 Pagesdirectly into an affected organ or tissue may be technically very difficult. Mostly, the affected areas do not differ much from the normal tissues in terms of temperature, local pH value and vascular permeability. The magnetic drug delivery also has limitations connected with blood flow rate in the target. Thus, the most natural and universal way to increase the affinity of a non-specific drug to the target site is by binding the drug with targeting moiety capable of specific recognition and binding atRead MoreHow Can Knowledge Management and Organisational Learning Used to Improve Hr Management Systems and Practices and Build Intellectual Capital and Competitive Advantage for the Future.2914 Words   |  12 Pages[pic] BACHELOR OF COMMERCE BUS 378 – KNOWLEDGE AND ORGANIZATIONAL LEARNING INDIVIDUAL ASSIGNMENT TABLE OF CONTENTS Page 1. Introduction 3 1.1 The Research Background 3 1.2 Limitation of the Report 4 1.3 Sources and Methods of Data Collection 4 2. Discussion 2.1 Knowledge Management (KM) 4 2.2 Organizational Learning (OL) 5 2.2.1 Double Loop Learning (DLL)Read MoreEvaluation Of Routine Immunization Performance Essay8403 Words   |  34 PagesChina [2]. It estimated that Pakistan has a child mortality of 86 per 1000 live birth. About 25% of these deaths are attributed to vaccine preventable diseases. In recent years the Pakistani routine immunization program faced many bottlenecks, which resulted in declining and stagnant coverage rates of all antigens leading to increasing vulnerability of children to vaccine preventable diseases. Last large measles outbreak was reported to kill more than 306 children [3]. Administrative coverage data showsRead MoreMergers Acquisitions in Pharma Industry21425 Words   |  86 Pages4.5 Research design 4.6 Qualitative research 4.7 Exploratory research 4.8 Data Collection Technique 4.8.1 Primary Data 4.8.2 Exploratory Research Design Secondary Data 4.8.3 Computerized Database 4.8.4 The Interview 4.9 Limitations of study References Chapter Five –Factors that support the research Objectives 5.1 Introduction 5.2 Foreign Direct Investment 5.2.1 Forms of FDI Chapter Summary Chapter Six-Research Findings Read MorePublic Health2465 Words   |  10 Pagesthe teaching-learning process by the health education/promotion profession. D) that the cost of health education/promotion is much less than other helping professions. Answer: C 17) The primary role of a health education specialist includes A) delivering health education/promotion programs and evaluating health education/promotion programs. B) developing health education/promotion programs for the people they serve and evaluating health education/promotion programs. C) assessing the needs and diagnosingRead MoreQuit Smoking Case Study Essay4989 Words   |  20 PagesThe task force also advises clinicians to ask all pregnant women, regardless of age, about tobacco use. Those who currently smoke should receive pregnancy-tailored counseling supplemented with self-help materials. Understanding the benefits and limitations of the available medications provides an important foundation for such a successful smoking cessation  program. Assess smoking history, level of addiction, and the health  status  of the patient. See the image below. After the assessment, interveneRead MoreSubstance Abuse Throughout Nursing : An Overview2377 Words   |  10 Pagesa weight which few but the brave can carry. To remove one’s self from the comfort of partiality and to place themselves into the hands of a sick patient without restraint is a beautiful ideal. It may seem flamboyant phrasing, but that symbolizes what a nurse is; becoming a servant to the needs of others before their own, someone who never stops choosing it. But sometimes the system fails even the strongest of soldiers; leading them down a dark and slippery path which holds the deceitful promiseRead More We Need Embryonic Stem Cell Research Essay2259 Words   |  10 Pagesremoved from embryos on or before that date (NIH Stem Cell Registry). So, since George W. Bush Administrations policy on Human Embryonic Stem Cell Research was added. The policy toward s embryonic stem cell research has placed extremely serious limitations on embryonic stem cell research in this country (American Thoracic Society Documents 1043-1045). Although it was estimated that 60-80 cell lines would be available, in fact only 22 cell lines produced before the policy announcement are actuallyRead MoreThe American Travel Health Nurses Association3195 Words   |  13 PagesTravel Health Nurses Association, n.d.). One of ATHNA?s main objectives is the development of professional competencies for travel medicine through increased access to educational opportunities. However, at this time ATHNA does not have a means of delivering educational content to the majority of its members due to the organization?s large geographic spread and scheduling difficulties. Goal To further the educational objectives of ATHNA, the goal of this thesis is to provide ATHNA?s Board with a

Golf, Outdoor Game In Which Individual Players Use Specially Designed Essay Example For Students

Golf, Outdoor Game In Which Individual Players Use Specially Designed Essay clubs to propel a small, hard ball over a field of play known as a course or links. The object of the game is to advance the ball around the course using as few strokes as possible. The Golf Course A golf course is divided into 18 sections, called holes. The standard course is about 6500 to 7000 yd (about 5900 to 6400 m). The individual holes may vary in length from 100 to 600 yd (about 90 to 550 m). Each hole has at one end a starting point known as a tee and, imbedded in the ground at the other end and marked by a flag, a cup or cylindrical container (also called a hole) into which the ball must be propelled in order to complete play at each hole. The cup is usually made of metal or plastic, 4.2 in (10.8 cm) in diameter, and at least 4 in (10 cm) deep. Play begins at the first tee, a level area of turf, generally raised slightly above the surrounding terrain. From here each player tries to drive the ball onto the fairway, or main part of the golf course, a carefully tended strip of land, 30 to 100 yd (about 27 to 90 m) wide, on which the grass has been cut to provide a good playing surface for the ball. On either side of the fairway is the rough, which consists of areas covered with long grass, bushes, or trees, and which sometimes contains sandy, rough, or marshy areas that compel golfers to use additional skill and judgment in playing their shots. In the absence of such natural obstacles, artificial hazards may be constructed. These include bunkers, also known as traps, which are hollows dug in the earth and usually filled with loose sand; mounds and other earthen embankments; and water hazards, such as ditches, creeks, ponds, or lakes. At the far end of the fairway from the tee is the putting green, an area of closely cropped gr ass surrounding the hole or cup. The smooth surface of the putting green is designed to facilitate the progress of the ball into the cup after the ball has been given a tap or gentle stroke known as a putt. Golf Strokes and Golf Clubs In addition to the putt, the specialized stroke used on the green, two main types of shots are used in playing each hole: the drive, which is a long shot from the tee onto the fairway; and the approach shot, which is the shot used to hit the ball onto the green. Both types demand great accuracy. Shots of various lengths are played with different clubs, according to the distance to be covered and the lie (position) of the ball. A standard set of 14 golf clubs (the maximum that may be carried in tournament play), is divided into two main types: those known as woods, with heads made of wood or metal; and those known as irons, with heads made of forged steel, usually chromium plated. The shafts of both types usually are made of metal and sometimes of fiberglass. Formerly, each club was known by a distinctive name, but today most are designated by numbers. The woods are customarily numbered 1 through 5, the irons 1 through 9. The putter, an iron, has retained i ts name. In addition to the numbered irons are the utility clubs, including the sand wedge and the pitching wedge, used on medium-range shots to loft the ball high into the air and limit its roll to a short distance after landing. The clubs are variously used in achieving distance, height, or accurate placement of the ball; the angle at which the striking surface is set on the shaft of the club determines the trajectory of the ball. For making drives and distance shots on the fairway, the woods (No. 1, or driver; No. 2; No. 3; No. 4; and No. 5) and the so-called long irons (No. 1, No. 2, and No. 3) are used. For the initial drive of each hole, the ball is teed up-that is, placed on a small wooden, rubber, or plastic peg, known as a tee, which the players carry with them. This lifts the ball at least 0.5 in (1.3 cm) off the ground, allowing the head of the club to strike the ball with maximum force. For long, low shots on the fairway, the No. 2 wood is used, and for long, high shots the No. 3, No. 4, and No. 5 woods are employed. Other approach shots to the green, generally of a shorter range, are played with irons. For even shorter approaches, known as chip shots, the same irons are used but with a shorter swi ng. The putter normally is used only on the green or the apron (a fringe of less smooth grass) of the green. Forms of Competition Two basic forms of competition exist in golf: match play and medal play (also known as stroke play). In match play the player (or, if more than one player, the team) taking the fewer number of strokes to sink the ball into any particular hole-called holing out-is the winner of the hole; the contest is won by the player or team winning the most holes. If each player or team takes the same number of strokes on any hole, the hole is said to be halved (tied). A final score of 9 and 8 in match play means that the winner was 9 holes ahead with only 8 left to play, sufficient to clinch victory in the match. When the match goes tied until the last hole, the winning score is 1 up. Is Justice Truly Blind EssayRules and Regulations The rules of play for golf are numerous and complex. They include a code of etiquette for behavior on the green. The game was originally played with a ball made of feathers tightly packed in a leather cover. About 1850 a ball made of gutta-percha came into use. Gutta-percha is a milky liquid, derived principally from Malaysian trees, that hardens after being boiled and cooled. About 1901 a ball with a rubber core enclosed in gutta-percha, similar to the ball in use today, was developed. The pitted surface of modern golf balls acts to stabilize flight. Golf balls must have a diameter of no less than 1.68 in (4.27 cm) and weigh not more than 1.62 oz (45.93 g). Governing Bodies The organizations that establish golf rules for the world are the Royal and Ancient Golf Club of St. Andrews and the United States Golf Association (USGA), founded in 1894 and located in Far Hills, New Jersey. Before 1913, golf in the United States was played chiefly by people of wealth. In 1913, however, after a former caddie from the United States named Francis Ouimet won a victory over two outstanding British professionals in the U.S. open championship tournament (open to amateurs and professionals), golf came to the attention of the American public in general. The Professional Golfers Association of America (PGA) was organized in 1916, and annual tournaments were started during the same year. The PGA is headquartered in Palm Beach Gardens, Florida. Currently, there are more than 23,000 members of the PGA, most of whom assist amateur players as club or resort instructors; and each year several hundred professional players tour the country competing in major tourna ments. The Ladies Professional Golf Association (LPGA), headquartered in Daytona Beach, Florida, numbers more than 800 club instructors, along with several hundred tournament players. Major professional tours include the PGA (for men), the LPGA (for women), and the Seniors tour (for men over the age of 50). Tournaments Each year many golf tournaments take place. The most important professional tournaments for men are the Masters, the U.S. Open, the British Open, and the PGA Championship. Collectively these four events form the grand slam of golf. Until 1960 the grand slam was considered to be the U.S. Open, the British Open, the U.S. Amateur, and the British Amateur, but with the increasing importance of professional golf in the mid-20th century, the Masters and the PGA Championship gained preeminence over the two amateur tournaments. However, the U.S. and British amateurs remain important events for nonprofessionals. For women the four professional tournaments forming the grand slam are the LPGA Championship, the U.S. Womens Open, the du Maurier Classic, and the Dinah Shore. The most important amateur events for women are the U.S. Womens Amateur and the British Womens Amateur Championship. International matches are also played. The Walker Cup (for men) and the Curtis Cup (for women) are contests between amateur golfers from the United States and Great Britain. The Ryder Cup (for men) and the Solheim Cup (for women) are contests between professional golfers from the United States and the rest of the world. (Before 1979 the Ryder Cup was contested only between American and British teams.) World competition tournaments for men also include the Eisenhower Cup for amateurs, the World Cup for professionals, and the Shun Nomura Trophy and the Francis H. I. Brown International Team Match Trophy for seniors. World competition tournaments for women also include the Espirito Santo Trophy. The most famous feat in the history of golf was achieved by the American amateur player Bobby Jones, who in 1930 achieved the grand slam of golf at the time by winning the British Open, the British Amateur, the U.S. Open, and the U.S. Amateur. No other player has ever won the grand slam in golf. One of the greatest women players of all time was Babe Didrikson Zaharias, an American who competed both as an amateur and as a professional. Other outstanding golfers include American players Walter Hagen, Gene Sarazen, Sam Snead, Ben Hogan, Arnold Palmer, Jack Nicklaus, Nancy Lopez, Kathy Whitworth, Tom Watson, JoAnne Carner, Pat Bradley, Lee Trevino, Patty Sheehan, Patty Berg, and Mickey Wright; British players Harry Vardon and Nick Faldo; Australian player Greg Norman; South African players Nick Price and Gary Player; and Spanish player Severiano Ballesteros. Other Forms of Golf Variations of golf, many of which can be played at night under lights, are developed from time to time: Miniature golf, a putting game on fancifully designed courses, became popular in the 1930s. Special putting greens and driving ranges combine practice and recreation. Pitch and putt is a shorter version of the standard game.